Clinical and sociodemographic factors associated with COVID-19 in non-hospitalized patients in southwest Goiás, Brazil, 2020 to 2022
PDF - en (English)

Palavras-chave

Cross-sectional studies
Public health
Respiratory tract infections
SARS-CoV-2

Como Citar

COSTA, L. F.; FARIA, R.; LIMONGI , J. E. Clinical and sociodemographic factors associated with COVID-19 in non-hospitalized patients in southwest Goiás, Brazil, 2020 to 2022. Sociedade & Natureza, [S. l.], v. 36, n. 1, 2024. DOI: 10.14393/SN-v36-2024-73720. Disponível em: https://seer.ufu.br/index.php/sociedadenatureza/article/view/73720. Acesso em: 3 jan. 2025.

Resumo

Considering that COVID-19 has had a major impact on public health around the world, we aimed to elucidate the clinical and sociodemographic characteristics of non-hospitalized patients in Quirinópolis, southwest Goiás, from 2020 to 2022. We performed a cross-sectional study, using secondary data on all suspected COVID-19 visits in Basic Health Units, bivariate data analysis and logistic regression. 18,036 suspected cases were registered with 56.1% laboratory confirmed. COVID-19 was concentrated in the central regions of the city and was more associated with the vaccinated group, which may be a reflection of the vaccine's protective effect on the worsening of symptoms. The final logistic regression model showed a higher risk of COVID-19 among mixed race (1.30; CI1:20-1.42) and young people as a protective factor (0.88; CI:0.78-0.98). Gustatory (2.78; IC:2.19-3.53) and olfactory (2.83; IC: 2.18-3.66) disorders, headache (1.11; IC: 1.02-1.11), fever (1.77; CI: 1.62-1.92) and cough (1.48; CI: 1.36-1.61) were also associated with a positive diagnosis of COVID-19. Only respiratory disease was found to be a risk factor, probably due to underreporting of other factors. COVID-19 is ubiquitous among non-hospitalized patients, with easy transmission in clusters and with striking demographic and clinical characteristics: Brown population, taste and olfactory disorders, headache, fever, cough and respiratory disease as risk factors; young people apparently as a protective factor and vaccinated more related to COVID-19 may be a reflection of the profile of the sampled group (outpatients). The ubiquity of SARS-CoV-2 in the municipality may be related to public policies promoting ineffective medicines and population behavior that contribute to the spread of the virus. In contrast, vaccines have proven effective in containing the severe disease. In the future, approaches to hospitalized patients are necessary to better understand the impacts of COVID-19.

https://doi.org/10.14393/SN-v36-2024-73720
PDF - en (English)

Referências

ALTMAN, J. D.; MINER, D. S.; LEE, A. A.; ASAY, A. E.; NIELSON, B. U.; ROSE, A. M.; HINTON, K.; POOLE, B. D. Factors affecting vaccine attitudes influenced by the COVID-19 pandemic. Vaccines, v. 11, n. 3, p. 516, 2023. https://doi.org/10.3390/vaccines11030516

ANSELIN L. Local indicators of spatial association − LISA. Geographical analysis, v. 27, n. 2, p. 93-115, 1995. https://doi.org/10.1111/j.1538-4632.1995.tb00338.x

ATKINS, J. L.; MASOLI, J. A. H.; DELGADO, J.; PILLING, L. C.; KUO, C. L.; KUCHEL, G. A.; MELZER, D. Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort. The Journals of Gerontology: Series A, v. 75, n. 11, p. 2224-2230, 2020. https://doi.org/10.1093/gerona/glaa183

BAETHGEN, L. F.; DA VEIGA, A. B. G.; SALVATO, R. S.; CARVALHO, T. G. D.; RISPOLI, T.; SCHIEFELBEIN, S. H.; MARTINS, L. G.; CEVS-COVID-19 TEAM; NUNES, Z. M. A.; SCHAURICH, A. P.; TIMM, L. N.; RAMOS, L. C.; BASTOS, C. G. M.; GREGIANINI, T. S. SARS-CoV-2 laboratory surveillance during the first year of the COVID-19 pandemic in southern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 56, p. e0146-2022, 2023. https://doi.org/10.1590/0037-8682-0146-2022

BIVAR, G. C. C.; DE AGUIAR, M. E. S. C.; SANTOS, R. V. C.; CARDOSO, P. R. G. COVID-19, the anti-vaccine movement and immunization challenges in Brazil: a review. Scientia Medica, v. 31, n. 1, p. 33, 2021. http://dx.doi.org/10.15448/1980-6108.2021.1.39425

CÂMARA G.; CARVALHO M. S.; CRUZ O. G.; CORREA V. Análise espacial de áreas. In: DRUCK S, CARVALHO MS, CÂMARA G, MONTEIRO AVM. et al (Eds). Análise espacial de dados geográficos. Brasília: EMBRAPA; 2004. p. 155- 205.

CIPOLLETTA, S.; ANDREGHETTI, G. R.; MIONI, G. Risk perception towards COVID-19: A systematic review and qualitative synthesis. International Journal of Environmental Research and Public Health, v. 19, n. 8, p. 4649, 2022. https://doi.org/10.3390/ijerph19084649

COSTA, L. F.; SOUZA, R. B.; DE OLIVEIRA, A. M. M.; EZEQUIEL, J. Seroprevalence of SARS-CoV-2 in southwest Goiás, Brazil, 2020: a population-based cross-sectional serological study. One Health & Implementation Research, v. 1, p. 31-42, 2021. https://doi.org/10.20517/ohir.2021.05

DAOUST, J. F. Elderly people and responses to COVID-19 in 27 Countries. PloS one, v. 15, n. 7, p. e0235590, 2020. https://doi.org/10.1371/journal.pone.0235590

FARRANHA, A. C.; RODRIGUES, L. C.; BATAGLIA, M. B. O direito à informação em saúde diante da base de dados do DATASUS: desafios jurídicos e políticos em tempos de COVID-19. Cadernos Ibero-Americanos de Direito Sanitário, Brasília, v. 11, n. 1, p. 32-47, jan./mar. 2022. https://doi.org/10.17566/ciads.v11i1.873

FOCOSI, D; QUIROGA, R.; MCCONNELL, S.; JOHNSON, M. C.; CASADEVALL, A. Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge. International journal of molecular sciences, v. 24, n. 3, p. 2264, 2023. https://doi.org/10.3390/ijms24032264

GARIBOTI, D. F.; DA SILVA JÚNIOR, F. M. R. Ethnic-racial disparity and mortality due to Covid-19: Case study of two medium-sized cities. Sociedade & Natureza, v. 34, p. e64009, 2022. https://doi.org/10.14393/SN-v34-2022-64009

GAYNOR, T. S.; WILSON, M. E. Social vulnerability and equity: The disproportionate impact of COVID‐19. Public administration review, v. 80, n. 5, p. 832-838, 2020. https://doi.org/10.1111/puar.13264

GOMES, I. A.; SOARES, P.; ROCHA, J. V.; GAMA, A.; LAIRES, P. A.; MONIZ, M.; PEDRO, A. R.; DIAS, S.; GOES, A. R.; LEITE, A.; NUNES, C. Factors associated with COVID-19 vaccine hesitancy after implementation of a mass vaccination campaign. Vaccines, v. 10, n. 2, p. 281, 2022. https://doi.org/10.3390/vaccines10020281

HALLAL, P. C.; HARTWIG, F. P.; HORTA, B. L.; SILVEIRA, M. F.; STRUCHINER, C. J.; VIDALETTI, L. P.; NEUMANN, N. A.; PELLANDA, L. C.; DELLAGOSTIN, O. A.; BURATTINI, M. N.; VICTORA, G. D.; MENEZES, A. M. B.; BARROS, F. C.; BARROS, A. J. D.; VICTORA, C. G. SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys. The Lancet Global Health, v. 8, n. 11, p. e1390-e1398, 2020. https://doi.org/10.1016/S2214-109X(20)30387-9

HANSON, S. W.; ABBAFATI, C.; AERTS, J. G.; AL-ALY, Z.; ASHBAUGH, C.; BALLOUZ, T.; BLYUSS, O.; BOBKOVA, P.; BONSEL, G.; BORZAKOVA, S. Global Burden of Disease Long COVID Collaborators. Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021. Jama, v. 328, n. 16, p. 1604-1615, 2022. https://doi.org/10.1001/jama.2022.18931

DEN HARTOG G.; VAN KASTEREN, P. B.; SCHEPP, R. M.; TEIRLINCK, A. C.; VAN DER KLIS, F. R.; VAN BINNENDIJK, R. S. Decline of RSV-specific antibodies during the COVID-19 pandemic. The Lancet Infectious Diseases, v. 23, n. 1, p. 23-25, 2023. https://doi.org/10.1016/S1473-3099(22)00763-0

HOPMAN, J.; ALLEGRANZI, B.; MEHTAR, S. Managing COVID-19 in Low- and Middle-Income Countries. Jama, v. 323, n. 16, p. 1549-1550, 2020. https://doi.org/10.1001/jama.2020.4169

KEMEI, J.; TULLI, M.; OLANLESI-ALIU, A.; TUNDE-BYASS, M.; SALAMI, B. Impact of the COVID-19 Pandemic on Black Communities in Canada. International Journal of Environmental Research and Public Health, v. 20, n. 2, p. 1580, 2023. https://doi.org/10.3390/ijerph20021580

DE LIMA, E. E. C.; DA COSTA, L. C. C.; SOUZA, R. F.; ROCHA, C. O. D. E.; ICHIHARA, M. Y. T. Presidential election results in 2018-2022 and its association with excess mortality during the 2020-2021 COVID-19 pandemic in Brazilian municipalities. Cadernos de Saúde Pública, v. 40, n. 5, 2024. https://doi.org/10.1590/0102-311XEN194723

MOHAMMED, I.; NAUMAN, A.; PAUL, P.; GANESAN, S.; CHEN, K. H.; JALIL, S. M. S.; JAOUNI, S. H.; KAWAS, H.; KHAN, W. A.; VATTOTH, A. L.; AL-HASHIMI, Y. A.; FARES, A.; ZEGHLACHE, R.; ZAKARIA, D. The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review. Human vaccines & immunotherapeutics, v. 18, n. 1, p. 2027160, 2022. https://doi.org/10.1080/21645515.2022.2027160

MORAWSKA, L.; CAO, J. Airborne transmission of SARS-CoV-2: The world should face the reality. Environment international, v. 139, p. 105730, 2020. https://doi.org/10.1016/j.envint.2020.105730

MOULIOU, D. S.; KONSTANTINOS, I. G. False-positive and false-negative COVID-19 cases: respiratory prevention and management strategies, vaccination, and further perspectives. Expert review of respiratory medicine, v. 15, n. 8, p. 993-1002, 2021. https://doi.org/10.1080/17476348.2021.1917389

NEHAB, M. F.; CAMACHO, K. G.; REIS, A. T.; DE FÁTIMA JUNQUEIRA-MARINHO, M.; ABRAMOV, D. M.; DE AZEVEDO, Z. M. A.; SALÚ, M. S.; DE VASCONCELOS, Z. F. M.; GOMES JUNIOR, S. C. S.; DA SILVA FILHO, O. C.; SALVADOR, P. T. C. O.; ALVES, K. Y. A.; DE CARVALHO, K. R. S.; MOORE, D. C. B. C. Willingness of Brazilian caregivers in having their children and adolescents vaccinated against Covid-19. Vaccine, v. 41, n. 3, p. 735-743, 2023. https://doi.org/10.1016/j.vaccine.2022.11.077

PAN, D.; SZE, S.; MINHAS, J. S.; BANGASH, M. N.; PAREEK, N.; DIVALL, P.; WILLIAMS, C. M. L.; OGGIONI, M. R.; SQUIRE I. B.; NELLUMS, L. B.; HANIF, W.; KHUNTI, K.; PAREEK, M. The impact of ethnicity on clinical outcomes in COVID-19: A systematic review. EClinicalMedicine, v. 23, 2020. https://doi.org/10.1016/j.eclinm.2020.100404

PATIÑO-ESCARCINA, J. E.; MEDINA, M. G. Vigilância em Saúde no âmbito da atenção primária para enfrentamento da pandemia da Covid-19: revisão documental. Saúde em Debate, v. 46, p. 119-130, 2022. https://doi.org/10.1590/0103-11042022E108

POTEAT, T.; MILLETT, G. A.; NELSON, L. E.; BEYRER, C. Understanding COVID-19 risks and vulnerabilities among Black communities in America: the lethal force of syndemics. Annals of epidemiology, v. 47, p. 1-3, 2020. https://doi.org/10.1016/j.annepidem.2020.05.004

RENDON, A. F. V.; VOLSCHAN, I. M.; PEREIRA, M. D. N.; PIMENTEL, A. D. F.; MONTEIRO, W. L.; OLIVEIRA, G. M. M. D. Marginalization, vulnerability and economic dynamics in COVID-19. International Journal of Cardiovascular Sciences, v. 34, p. 319-323, 2021. https://doi.org/10.36660/ijcs.20210029

STEIN, R.; ZAR, H. J. RSV through the COVID‐19 pandemic: Burden, shifting epidemiology, and implications for the future. Pediatric Pulmonology, v. 58, n. 6, p. 1631-1639, 2023. https://doi.org/10.1002/ppul.26370

STOKEL-WALKER, C. What do we know about covid vaccines and preventing transmission? bmj, v. 376, 2022. https://doi.org/10.1136/bmj.o298

STRUYF, T.; DEEKS, J. J.; DINNES, J.; TAKWOINGI, Y.; DAVENPORT, C.; LEEFLANG, M. M.; SPIJKER, R.; LOTTY, L.; EMPERADOR, D.; DOMEN, J.; TANS, A.; JANSSENS, S.; WICKRAMASINGHE, D.; LANNOY, V.; HORN, S. R. A.; VAN DEN BRUEL, A. Cochrane COVID-19 Diagnostic Test Accuracy Group. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19. Cochrane database of systematic reviews, n. 5, 2022. https://doi.org/10.1002/14651858.CD013665.pub3

TALLEI, T. E.; ALHUMAID, S.; ALMUSA, Z.; FATIMAWALI; KUSUMAWATY, D.; ALYNBIAWI, A.; ALSHUKAIRI, A. N.; RABAAN, A. A. Update on the omicron sub‐variants BA. 4 and BA. 5. Reviews in medical virology, v. 33, n. 1, p. e2391, 2023. https://doi.org/10.1002/rmv.2391

WANG, B.; LI, R.; LU, Z.; HUANG, Y. Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. Aging (albany NY), v. 12, n. 7, p. 6049, 2020. https://doi.org/10.18632/aging.103000

YAN, C. H.; FARAJI, F.; PRAJAPATI, D. P.; OSTRANDER, B. T.; DECONDE, A. S. Self-reported olfactory loss associates with outpatient clinical course in COVID-19. In: International forum of allergy & rhinology, v. 10, n. 7, p. 821-831. 2020. https://doi.org/10.1002/alr.22592

ZHU, J.; JI, P.; PANG, J.; ZHONG, Z.; LI, H.; HE, C.; ZHANG, J.; ZHAO, C. Clinical characteristics of 3062 COVID‐19 patients: a meta‐analysis. Journal of medical virology, v. 92, n. 10, p. 1902-1914, 2020. https://doi.org/10.1002/jmv.25884

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 2023 Lourenço Faria Costa, Rivaldo Faria, Jean Ezequiel Limongi

Downloads

Não há dados estatísticos.

Métricas

Carregando Métricas ...