Effects of prebiotic intake on glycemia and serum cholesterol concentration in obese and eutrophic dogs: a systematic review

Tatiane Caroline Leite; Filipe Otávio Frederico Marcelino; Eric Francelino Andrade; Márcio Gilberto Zangerônimo; Luciano José Pereira

doi:10.14393/BJ-v40n0a2024-71478

Authors

Tatiane Caroline Leite Universidade Federal de Lavras
Filipe Otávio Frederico Marcelino Universidade Federal de Lavras
Eric Francelino Andrade Universidade Federal de Lavras https://orcid.org/0000-0002-9253-3108
Márcio Gilberto Zangerônimo Universidade Federal de Lavras https://orcid.org/0000-0002-3530-9345
Luciano José Pereira Universidade Federal de Lavras https://orcid.org/0000-0002-0502-2554

DOI:

https://doi.org/10.14393/BJ-v40n0a2024-71478

Keywords:

Animal Nutrition, Prebiotics, Systematic Reviews as Topic.

Abstract

Sedentary behavior and low physical stimulation in companion animals have increased obesity and related metabolic disorders. Dietary fibers, such as prebiotic polysaccharides, are potential adjunct therapies for these conditions. This systematic review evaluated the effects of prebiotic intake on blood glucose and serum cholesterol levels in dogs. Using the PICOS strategy, we focused on eutrophic and obese dogs treated with prebiotics (Intervention) versus placebo diets (Comparison) in randomized clinical trials (Study design). The outcomes assessed were blood glucose and serum cholesterol concentrations. Two reviewers independently searched five databases and grey literature, assessing bias with the SYRCLE protocol. From 2,518 articles, 22 were pre-selected for full-text review, and nine met the inclusion criteria. Qualitative analysis revealed that prebiotic intake significantly reduced serum cholesterol in 57% of studies, particularly in non-obese dogs (75%), without exceeding physiological limits. However, blood glucose levels were unaffected in most studies (71%). The studies demonstrated low risk of bias, though blinding procedures were often poorly described. Due to study heterogeneity, meta-analysis was not feasible. We concluded that prebiotic ingestion effectively reduces serum cholesterol in dogs, with minimal impact on blood glucose levels.

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References

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