Chemical composition, antibacterial and modulatory action of the essential oil of Croton rhamnifolioides leaves Pax and Hoffman

Authors

  • Cinara Soares Vidal Universidade Regional do Cariri
  • Cícera Datiane Morais Oliveira-Tintino Universidade Regional do Cariri
  • Saulo Relison Tintino Universidade Regional do Cariri
  • Hericka Bruna Figueiredo Galvão University of London
  • José Galberto Martins da Costa Universidade Regional do Cariri
  • Henrique Douglas Melo Coutinho Universidade Regional do Cariri
  • Irwin Rose Alencar de Menezes Universidade Regional do Cariri

DOI:

https://doi.org/10.14393/BJ-v32n1a2016-33918

Keywords:

Croton rhamnifolioides, modulation, essential oil, terpenes

Abstract

The species Croton rhamnifolioides is a shrub popularly known as "quebra faca", utilized in teas or infusions for the treatment of gastrointestinal disorders as ulcers, gastric discomfort, vomiting and hemorrhagic diarrhea. This work has as its main objective to evaluate the chemical composition of the essential oil of the Croton rhamnifolioides leaves (EOC), antibacterial activity and modulatory activity of antibiotic resistance, against bacterial strains of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and, and antifungal activity against Candida albicans, Candida krusei and Candida tropicalis. The chemical composition was determined through chromatography with a gas phase coupled with mass spectrometry (CG/MS), whereas antimicrobial activity and modulation were determined by microdilution assay. The chemical composition of the oil revealed 21 compounds, with the major compounds being spathulenol (22.46%) and 1,8-cineol (18.32%). The antimicrobial activity was not significant with MIC>1024 µg/mL, however, was observed a synergistic interference when essential oil associated with the antibiotics aminoglycoside and β-lactam, and the antifungal polyene.

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Published

2016-12-06

How to Cite

VIDAL, C.S., MORAIS OLIVEIRA-TINTINO, C.D., TINTINO, S.R., GALVÃO, H.B.F., COSTA, J.G.M. da, COUTINHO, H.D.M. and MENEZES, I.R.A. de, 2016. Chemical composition, antibacterial and modulatory action of the essential oil of Croton rhamnifolioides leaves Pax and Hoffman . Bioscience Journal [online], vol. 32, no. 6, pp. 1632–1643. [Accessed6 December 2022]. DOI 10.14393/BJ-v32n1a2016-33918. Available from: https://seer.ufu.br/index.php/biosciencejournal/article/view/33918.

Issue

Section

Biological Sciences