Effects of Rooibos (Aspalathus linearis) on the Testicular Parenchyma of Adult BALB/C Mice Submitted to a Hypercaloric Diet

Authors

  • Hilara Niemeyer Ruas Universidade Federal do Triângulo Mineiro
  • João Vitor Lopes-Ferreira Universidade Federal do Triângulo Mineiro
  • Fernanda Carolina Ribeiro Dias Universidade Federal do Triângulo Mineiro https://orcid.org/0000-0002-6530-4684
  • Maria Emília Soares Martins dos Santos Universidade Federal do Triângulo Mineiro https://orcid.org/0000-0001-8922-0867
  • Angelica de Oliveira Gomes Universidade Federal do Triângulo Mineiro
  • Mariella Bontempo Freitas Universidade Federal de Viçosa https://orcid.org/0000-0001-5132-242X
  • Marcos de Lucca Moreira Gomes Universidade Federal do Triângulo Mineiro https://orcid.org/0000-0003-4397-4609

DOI:

https://doi.org/10.14393/BJ-v39n0a2023-64537

Keywords:

High fat diet, Obesity, Oxidative stress, Reproduction, Testis.

Abstract

Oxidative stress due to obesity plays a detrimental role in the testicular microenvironment and sperm parameters. We explored the impact of a hypercaloric diet in male BALB/c mice as a condition to trigger damage to the spermatogenic process and the antioxidant effect of Aspalathus linearis as well. We used a hypercaloric diet in animals divided into 3 groups: Control, Hypercaloric diet control (HC) and Hypercaloric diet and Rooibos infusion (HCR). Morphometric parameters, enzyme dosages, cell viability, and tubular histopathology were evaluated. Body weight increased in HCR animals at weeks 3, 4, and 8. We found a reduction in seminiferous epithelium height, with an increase in the tubular diameter of the HCR group. Catalase levels were lower in HC and HCR, while carbonyl protein was decreased in HC. We estimate that it induces oxidative stress (OS) capable of affecting the seminiferous epithelium and that the infusion of A. linearis does not demonstrate a potential benefit in cell preservation.

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Published

2023-02-24

How to Cite

NIEMEYER RUAS, H., LOPES-FERREIRA, J.V., DIAS, F.C.R., SANTOS, M.E.S.M. dos, GOMES, A. de O., FREITAS, M.B. and GOMES, M. de L.M., 2023. Effects of Rooibos (Aspalathus linearis) on the Testicular Parenchyma of Adult BALB/C Mice Submitted to a Hypercaloric Diet. Bioscience Journal [online], vol. 39, pp. e39030. [Accessed18 June 2024]. DOI 10.14393/BJ-v39n0a2023-64537. Available from: https://seer.ufu.br/index.php/biosciencejournal/article/view/64537.

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Biological Sciences