Association between TSH status and prevalence of miscarriages and stillbirth

Afshan Kaleem; Rabail Javed; Kashmala Khalil; Mehwish  Iqtedar; Roheena Abdullah; Lubna  Riaz; Nadeem  Ahmad; Farheen  Aslam

doi:10.14393/BJ-v37n0a2021-53854

Authors

Afshan Kaleem Lahore College for Women University https://orcid.org/0000-0002-3972-0051
Rabail Javed Shaikh Zayed Medical Complex https://orcid.org/0000-0001-7041-8726
Kashmala Khalil Lahore College for Women University https://orcid.org/0000-0003-2472-1067
Mehwish Iqtedar Lahore College for Women University https://orcid.org/0000-0002-2350-3431
Roheena Abdullah Lahore College for Women University https://orcid.org/0000-0003-3932-6297
Lubna Riaz Shaikh Zayed Medical Complex https://orcid.org/0000-0003-2206-3355
Nadeem Ahmad Sialkot Medical College https://orcid.org/0000-0002-0109-8092
Farheen Aslam Lahore College for Women University https://orcid.org/0000-0003-4380-2401

DOI:

https://doi.org/10.14393/BJ-v37n0a2021-53854

Keywords:

Hypo-/hyperthyroidism, Iodine Intake, IUD, Pregnant Females, TSH.

Abstract

Thyroid hormones play a significant role in normal human body growth. Abnormalities in thyroid stimulating hormone (TSH) levels can result in pregnancy loss due to miscarriages and intrauterine death (IUD). The objective of the study was to assess the levels of association of thyroid stimulating hormone with miscarriages and IUD. The descriptive study involving 110 samples between 18-40 years of age fulfilling inclusion criteria were sampled for TSH testing (2ml blood) after attaining their written informed consent. The mean age of participants was 29.49±4.26 year. The prevalence of hypothyroidism and hyperthyroidism was 3.64% and 2.73%, respectively. Complications like gestational hypertension, depression and oligomenorrhea were found prevalent in these females. Majority of females were taking high/low iodine than recommended iodine level (150mcg). This work shows that there is a significant association between pregnancy loss and disturbed TSH levels among pregnant females.

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