In vitro antimicrobial activity of mexican plants on bovine mastitis bacteria: preliminary studies


  • Mariana Macías Alonso Instituto Politécnico Nacional
  • Julio C. López Salazar La Casa del Bosque A.C. Guanajuato
  • Soraya Osegueda Robles Instituto Politécnico Nacional
  • Iván Córdova Guerrero Universidad Autónoma de Baja California
  • Fernanda Ledezma García Instituto Politécnico Nacional
  • Joaquín G. Marrero Instituto Politécnico Nacional



Antibiotic, Ethnomedicines, Dairy animals, Infectious disease, mastitis


The present study aimed to evaluate the efficacy of traditionally used antibacterial plants (Euphorbia prostrata, Schinus molle, Brickellia veronicaefolia and Lepidium virginicum) in Santa Rosa Range in Guanajuato against major mastitis-causing pathogens. The selected plants were phytochemically screened for alkaloids, flavonoids, polyphenols, saponins, anthraquinone, cardiac glycosides, steroids and terpenoids. Moreover, to achieve the main purpose of the present research, extracts of selected plants were tested for in vitro antibacterial activity against Staphylococcus aureus, Escherichia coli, Shigella spp., Bacillus subtilis, Clavibacter spp., Proteus vulgaris and Salmonella spp. All these bacterial were isolated from clinical mastitis in dairy cows. The results indicated that the ethanolic extract of the aerial part of L. virginicum exhibited the strongest antimicrobial activity, and it could be potential candidate specie for the development of novel veterinary drugs with low cost and fewer side effects.


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How to Cite

MACÍAS ALONSO, M.., LÓPEZ SALAZAR, J.C.., OSEGUEDA ROBLES, S.., CÓRDOVA GUERRERO, I.., LEDEZMA GARCÍA, F.. and JOAQUÍN G. MARRERO, 2020. In vitro antimicrobial activity of mexican plants on bovine mastitis bacteria: preliminary studies. Bioscience Journal [online], vol. 36, no. 1, pp. 183–190. [Accessed25 April 2024]. DOI 10.14393/BJ-v36n1a2020-42137. Available from:



Agricultural Sciences